Hadi Sadiqi*, Ghulam Mohammad Amiri**, Qasem Rezaee**, Mustafa Ahmadzada**, Ghulam Haider Jamalzada
Background: Preeclampsia is a leading cause of maternal mortality, particularly in low- and middle-income countries (LMICs) where access to healthcare services is limited. Despite significant advancements in prenatal care in high-income countries, preeclampsia continues to challenge healthcare systems globally, especially in regions with limited resources. Methodology: This analytical study examined recent literature and epidemiological data to assess the incidence, prevalence, and impact of preeclampsia on maternal mortality. Data were collected from studies spanning high- and low-income regions to identify risk factors, complications, and regional disparities in healthcare access. Results: Preeclampsia affects approximately 3-10% of all pregnancies worldwide, with higher rates observed in LMICs. Advanced maternal age, obesity, hypertension, and diabetes are significant risk factors, exacerbated by socioeconomic constraints in resource-poor settings. Preeclampsia accounts for 10-15% of maternal deaths, with LMICs experiencing higher mortality due to limited emergency obstetric care and delayed treatment. Preventive strategies such as routine screenings and early interventions have reduced complications and improved maternal outcomes in high-income settings but remain underutilized in LMICs.